SCHEMBL23965671

SCHEMBL23965671

CCC/C=C(\C(=O)OC)c1ccccc1CO/N=C(\C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.44
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
PPARA Q07869 4/20 0.39
PPARG P37231 4/20 0.39
S1PR1 P21453 5/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23969511 0.92 S1PR1 (0.40) HIF1AHPGDL3MBTL1MAPK1PPARA
SCHEMBL23969485 0.87 HIF1A (0.46) HIF1AL3MBTL1HTTPPARAPPARG
SCHEMBL23978133 0.85 HPGD (0.39) HIF1AHPGDL3MBTL1LMNAMAPK1
SCHEMBL7558159 0.78 HIF1A (0.67) HIF1AHPGDL3MBTL1LMNAMAPK1
SCHEMBL23965585 0.78 GAA (0.41) HIF1AHPGDL3MBTL1LMNAPPARA
SCHEMBL23978035 0.78 HIF1A (0.35) HIF1ALMNAMAPK1PPARGS1PR1
SCHEMBL23969524 0.78 S1PR1 (0.37) HIF1AHPGDL3MBTL1LMNAPPARA
SCHEMBL23969523 0.77 HPGD (0.37) HPGDL3MBTL1LMNANPC1RAB9A
SCHEMBL23965598 0.77 MAPT (0.37) HIF1AHPGDL3MBTL1LMNAPPARA
SCHEMBL23967970 0.77 S1PR1 (0.41) HIF1AHPGDLMNAPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903583-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III BASF SE (DE) 2021-11-03 EP disclosed