SCHEMBL23969523

SCHEMBL23969523

CCC/C=C(\C(=O)NC)c1ccccc1CO/N=C(\C)c1ccccc1OC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.37
LMNA P02545 2/20 0.36
CTSD P07339 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
STAT3 P40763 2/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23979245 0.80 HIF1A (0.44) HPGDLMNACTSDMEN1KMT2A
SCHEMBL23965671 0.77 HIF1A (0.44) HPGDLMNAMEN1KMT2ANPC1
SCHEMBL23965672 0.75 HIF1A (0.35)
SCHEMBL23965716 0.74 GAA (0.40) HPGDLMNANPC1RAB9AL3MBTL1
SCHEMBL23969511 0.74 S1PR1 (0.40) HPGDNPC1RAB9AL3MBTL1
SCHEMBL23967899 0.73 ALDH1A1 (0.34) LMNAKMT2ANPC1RAB9A
SCHEMBL23972053 0.70 HPGD (0.36) HPGDLMNACTSDSTAT3NPC1
SCHEMBL13703755 0.68 L3MBTL1 (0.45) HPGDLMNACTSDNPC1RAB9A
SCHEMBL20822604 0.68 HIF1A (0.38) HPGDLMNA
SCHEMBL23971955 0.68 HIF1A (0.44) MEN1KMT2ANPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903582-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II BASF SE (DE) 2021-11-03 EP disclosed