Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638165 | 1.00 | NPC1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638193 | 0.89 | NPC1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638268 | 0.82 | SMN1; SMN2 (0.56) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638197 | 0.82 | SMN1; SMN2 (0.56) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638195 | 0.82 | SMN1; SMN2 (0.56) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638217 | 0.82 | SMN1; SMN2 (0.62) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL31349457 | 0.81 | NPC1 (0.61) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638253 | 0.81 | NPC1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638295 | 0.81 | MAPT (0.54) | NPC1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL21638258 | 0.80 | SMN1; SMN2 (0.51) | NPC1RAB9AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | FUJIFILM CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | HAVCR2, HBS1L, PHKB | NPC1 1739/4885RAB9A 2878/4885MAPT 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.