Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965749 | 0.93 | PPARG (0.53) | MEN1KMT2AALOX15TSHRPPARD | |
| SCHEMBL21669173 | 0.80 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2LMNANPC1 | |
| SCHEMBL21511146 | 0.79 | MEN1 (0.47) | MEN1KMT2AALOX15TSHRSMN1; SMN2 | |
| SCHEMBL10387972 | 0.78 | CYP3A4 (0.52) | MEN1KMT2AALOX15TSHRPPARG | |
| SCHEMBL21675474 | 0.77 | MEN1 (0.46) | MEN1KMT2AALOX15TSHRSMN1; SMN2 | |
| SCHEMBL18873116 | 0.77 | MEN1 (0.46) | MEN1KMT2AALOX15TSHRPPARG | |
| SCHEMBL18997843 | 0.77 | NR1I2 (0.51) | MEN1KMT2AALOX15TSHRSMN1; SMN2 | |
| SCHEMBL23185838 | 0.76 | KMT2A (0.47) | MEN1KMT2AALOX15TSHRSMN1; SMN2 | |
| SCHEMBL23016646 | 0.76 | TSHR (0.46) | MEN1KMT2AALOX15TSHRSMN1; SMN2 | |
| SCHEMBL11750957 | 0.75 | HDAC1 (0.46) | ALOX15TSHRPPARDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | FUJIFILM CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | HAVCR2, HBS1L, PHKB | MEN1 2649/4885KMT2A 2334/4885ALOX15 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.