SCHEMBL23965880

SCHEMBL23965880

N#Cc1ccc(-c2ccc(-n3c4ccccc4c4cc(C(F)(F)F)ccc43)c(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)ccc3-n3c4ccccc4c4cc(C(F)(F)F)ccc43)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.40
DGAT1 O75907 1/20 0.39
SOAT1 P35610 1/20 0.39
KCNH2 Q12809 1/20 0.39
ABCG2 Q9UNQ0 11/20 0.38
ABCB1 P08183 5/20 0.38
ABCC1 P33527 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
DHODH Q02127 1/20 0.35
PDPK1 O15530 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20910794 0.97 KIF11 (0.39) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL21364838 0.97 KIF11 (0.42) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL21364353 0.95 KIF11 (0.38) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL23965891 0.95 ABCG2 (0.37) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL22243019 0.95 CYP1A2 (0.37) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL20910692 0.94 KIF11 (0.37) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL27022492 0.94 KIF11 (0.38) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL20910792 0.94 KIF11 (0.41) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL21365102 0.94 ABCG2 (0.36) KIF11DGAT1SOAT1KCNH2ABCG2
SCHEMBL21365035 0.93 CYP1A2 (0.42) ABCG2PTGDR2MEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161836-B2 Organic molecules for optoelectronic devices CYNORA GMBH (DE) 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161836-B2 Organic molecules for optoelectronic devices OR10J3, OR51E2, OCIAD2 KIF11 2121/4885DGAT1 908/4885SOAT1 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.