SCHEMBL23965912

SCHEMBL23965912

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc(-c2ccc(C#N)cc2)cc1-c1cc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)ccc1-n1c2ccc(C(C)(C)C)cc2c2cc(C(C)(C)C)ccc21

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.43
ABCG2 Q9UNQ0 17/20 0.40
ABCB1 P08183 11/20 0.40
ABCC1 P33527 4/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
KDM1A O60341 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23965911 0.97 KIF11 (0.40) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL22137244 0.97 KIF11 (0.42) KIF11ABCG2ABCB1ABCC1KDM1A
SCHEMBL21364789 0.96 KIF11 (0.40) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL21364318 0.96 KIF11 (0.40) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL21364320 0.95 KIF11 (0.40) KIF11ABCG2ABCB1ABCC1KDM1A
SCHEMBL27015813 0.95 KIF11 (0.40) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL21364358 0.95 ABCG2 (0.40) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL20794287 0.95 CYP1A2 (0.39) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL22137221 0.94 KIF11 (0.40) KIF11ABCG2ABCB1ABCC1MEN1
SCHEMBL21364983 0.93 KIF11 (0.38) KIF11ABCG2ABCB1ABCC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161836-B2 Organic molecules for optoelectronic devices CYNORA GMBH (DE) 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161836-B2 Organic molecules for optoelectronic devices OR10J3, OR51E2, OCIAD2 KIF11 2121/4885ABCG2 3275/4885ABCB1 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.