Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914852 | 0.96 | XDH (0.43) | XDHS1PR2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL23914602 | 0.83 | S1PR2 (0.41) | S1PR2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL23915221 | 0.71 | S1PR2 (0.77) | XDHS1PR2 | |
| SCHEMBL23909059 | 0.71 | S1PR2 (0.42) | XDHS1PR2 | |
| SCHEMBL23908843 | 0.69 | XDH (0.39) | XDH | |
| SCHEMBL23909036 | 0.69 | S1PR2 (0.57) | XDHS1PR2SMN1; SMN2 | |
| SCHEMBL23914609 | 0.69 | XDH (0.38) | XDH | |
| SCHEMBL22199021 | 0.68 | XDH (0.47) | XDH | |
| SCHEMBL20376280 | 0.67 | S1PR2 (0.47) | S1PR2 | |
| SCHEMBL22184886 | 0.65 | IDH1 (0.55) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |