Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 17/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909024 | 0.89 | S1PR2 (0.59) | S1PR2KCNH2KMOP2RX3 | |
| SCHEMBL23914568 | 0.89 | S1PR2 (0.58) | S1PR2KCNH2KMOP2RX3 | |
| SCHEMBL23908923 | 0.83 | S1PR2 (0.51) | S1PR2KCNH2KMOP2RX3 | |
| SCHEMBL23914587 | 0.82 | S1PR2 (0.50) | S1PR2KCNH2KMOP2RX3 | |
| SCHEMBL23908856 | 0.75 | S1PR2 (0.67) | S1PR2KCNH2KMO | |
| SCHEMBL23908757 | 0.72 | S1PR2 (1.00) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23915483 | 0.67 | S1PR2 (0.85) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23908812 | 0.67 | S1PR2 (0.57) | S1PR2 | |
| SCHEMBL23908813 | 0.66 | S1PR2 (0.81) | S1PR2 | |
| SCHEMBL23909068 | 0.65 | KMO (0.37) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |