Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 14/20 | 0.84 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908925 | 0.92 | S1PR2 (1.00) | S1PR2 | |
| SCHEMBL23908926 | 0.91 | S1PR2 (0.86) | S1PR2TP53POLB | |
| SCHEMBL23914706 | 0.89 | S1PR2 (0.82) | S1PR2TP53 | |
| SCHEMBL23966542 | 0.89 | S1PR2 (0.82) | S1PR2POLB | |
| SCHEMBL23914728 | 0.88 | S1PR2 (0.80) | S1PR2TP53POLB | |
| SCHEMBL23966875 | 0.87 | S1PR2 (0.74) | S1PR2TP53MAPT | |
| SCHEMBL23908745 | 0.87 | S1PR2 (0.73) | S1PR2MAPT | |
| SCHEMBL23908915 | 0.86 | S1PR2 (0.72) | S1PR2TP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL23914855 | 0.85 | S1PR2 (0.77) | S1PR2TP53 | |
| SCHEMBL23908860 | 0.84 | S1PR2 (0.81) | S1PR2RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |