Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 16/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908745 | 0.91 | S1PR2 (0.73) | S1PR2NPSR1THRBMAPT | |
| SCHEMBL23908915 | 0.87 | S1PR2 (0.72) | S1PR2NPSR1MAPTTP53 | |
| SCHEMBL23966571 | 0.87 | S1PR2 (0.84) | S1PR2MAPTTP53 | |
| SCHEMBL23908925 | 0.85 | S1PR2 (1.00) | S1PR2 | |
| SCHEMBL23908926 | 0.83 | S1PR2 (0.86) | S1PR2TP53 | |
| SCHEMBL23908975 | 0.82 | S1PR2 (0.76) | S1PR2 | |
| SCHEMBL23914706 | 0.81 | S1PR2 (0.82) | S1PR2TP53 | |
| SCHEMBL23966542 | 0.81 | S1PR2 (0.82) | S1PR2 | |
| SCHEMBL23908845 | 0.81 | S1PR2 (0.73) | S1PR2 | |
| SCHEMBL23914728 | 0.80 | S1PR2 (0.80) | S1PR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |