Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966553 | 0.93 | S1PR2 (0.52) | S1PR2KDM4EHSD17B10POLBMAPT | |
| SCHEMBL23908878 | 0.92 | S1PR2 (0.64) | S1PR2KDM4EHSD17B10POLBMAPT | |
| SCHEMBL23966895 | 0.88 | S1PR2 (0.48) | S1PR2KDM4EHSD17B10POLB | |
| SCHEMBL23966648 | 0.87 | S1PR2 (0.56) | S1PR2SMN1; SMN2GAA | |
| SCHEMBL23966611 | 0.86 | S1PR2 (0.53) | S1PR2MAPTSMN1; SMN2 | |
| SCHEMBL23966599 | 0.84 | S1PR2 (0.51) | S1PR2MAPTSMN1; SMN2 | |
| SCHEMBL23908730 | 0.84 | S1PR2 (0.61) | S1PR2KDM4EHSD17B10POLBMAPT | |
| SCHEMBL23966606 | 0.84 | S1PR2 (0.61) | S1PR2KDM4EHSD17B10POLBMAPT | |
| SCHEMBL23909046 | 0.84 | S1PR2 (0.61) | S1PR2KDM4EHSD17B10POLBMAPT | |
| SCHEMBL23966618 | 0.84 | S1PR2 (0.52) | S1PR2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |