Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 10/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908730 | 1.00 | S1PR2 (0.61) | S1PR2POLBCYP2C19KDM4EHSD17B10 | |
| SCHEMBL23908878 | 0.92 | S1PR2 (0.64) | S1PR2POLBKDM4EHSD17B10MAPT | |
| SCHEMBL23914585 | 0.89 | S1PR2 (0.68) | S1PR2POLBKDM4EHSD17B10MEN1 | |
| SCHEMBL23909046 | 0.88 | S1PR2 (0.61) | S1PR2POLBKDM4EHSD17B10MEN1 | |
| SCHEMBL23909089 | 0.87 | S1PR2 (0.78) | S1PR2CYP2C19ALOX15 | |
| SCHEMBL23908736 | 0.87 | S1PR2 (0.61) | S1PR2POLBKDM4EHSD17B10MEN1 | |
| SCHEMBL23908790 | 0.87 | S1PR2 (0.61) | S1PR2POLBKDM4EHSD17B10MAPT | |
| SCHEMBL23908809 | 0.87 | S1PR2 (0.59) | S1PR2POLBKDM4EHSD17B10MAPT | |
| SCHEMBL23908986 | 0.87 | S1PR2 (0.61) | S1PR2POLBKDM4EHSD17B10MAPT | |
| SCHEMBL23966642 | 0.86 | S1PR2 (0.63) | S1PR2POLBKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |