Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 9/20 | 0.51 |
| ▸ | QPCT | Q16769 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908936 | 0.83 | S1PR2 (0.67) | S1PR2QPCT | |
| SCHEMBL23915473 | 0.83 | S1PR2 (0.67) | S1PR2AKR1B1 | |
| SCHEMBL23908969 | 0.77 | S1PR2 (0.67) | S1PR2 | |
| SCHEMBL23909089 | 0.77 | S1PR2 (0.78) | S1PR2AKR1B1 | |
| SCHEMBL23966579 | 0.76 | S1PR2 (0.75) | S1PR2 | |
| SCHEMBL23908794 | 0.76 | S1PR2 (0.62) | S1PR2AKR1B1 | |
| SCHEMBL23908767 | 0.75 | S1PR2 (0.75) | S1PR2 | |
| SCHEMBL23908744 | 0.75 | S1PR2 (0.80) | S1PR2AKR1B1 | |
| SCHEMBL23966612 | 0.75 | S1PR2 (0.58) | S1PR2 | |
| SCHEMBL23908861 | 0.73 | S1PR2 (0.76) | S1PR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |