Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 7/20 | 0.32 |
| ▸ | HTR2B | P41595 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23915570 | 0.84 | CNR2 (0.39) | CNR2SCN9AHTR2CHTR2BHTR2A | |
| SCHEMBL16738735 | 0.78 | MCHR1 (0.42) | SCN9AHTR2CAAK1CDK2THRA | |
| SCHEMBL16650978 | 0.71 | RIPK1 (0.41) | HTR2CHTR2BHTR2ARIPK1MCHR1 | |
| SCHEMBL31027311 | 0.70 | SCD (0.42) | CNR2SCN9AHTR2CHTR2BHTR2A | |
| SCHEMBL21957402 | 0.70 | SCD (0.42) | CNR2SCN9AHTR2CHTR2BHTR2A | |
| SCHEMBL23966847 | 0.70 | AAK1 (0.40) | CNR2SCN9AHTR2CHTR2BHTR2A | |
| SCHEMBL5241392 | 0.69 | CNR2 (0.38) | CNR2SCN9AHTR2CHTR2B | |
| SCHEMBL23966507 | 0.68 | KDM4E (0.39) | HTR2CHTR2BHTR2ACDK2RIPK1 | |
| SCHEMBL12891258 | 0.67 | HRH3 (0.39) | PIM1PIM2THRATHRB | |
| SCHEMBL15541723 | 0.67 | SLC6A4 (0.42) | CNR2SCN9APIM1PIM2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |