Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23915385 | 0.94 | PARP1 (0.35) | PARP1TNKSPARP6TNKS2PARP2 | |
| SCHEMBL23915393 | 0.85 | PARP1 (0.35) | PARP1TNKSPARP6TNKS2PARP2 | |
| SCHEMBL23908886 | 0.84 | PARP1 (0.36) | PARP1TNKSPARP6TNKS2PARP2 | |
| SCHEMBL23966811 | 0.82 | PARP1 (0.36) | PARP1TNKSPARP6TNKS2PARP2 | |
| SCHEMBL23915383 | 0.81 | PARP1 (0.35) | PARP1TNKSPARP6TNKS2PARP2 | |
| SCHEMBL23915442 | 0.76 | S1PR2 (0.35) | — | |
| SCHEMBL23914724 | 0.75 | S1PR2 (0.36) | — | |
| SCHEMBL23915601 | 0.75 | S1PR2 (0.36) | — | |
| SCHEMBL23915621 | 0.75 | S1PR2 (0.41) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23915472 | 0.72 | XDH (0.32) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |