Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909123 | 0.74 | S1PR2 (0.40) | S1PR2HTTHSD17B10 | |
| SCHEMBL23914653 | 0.69 | RHEB (0.41) | S1PR2S1PR1ACACB | |
| SCHEMBL23908833 | 0.67 | S1PR2 (0.44) | S1PR2 | |
| SCHEMBL23909089 | 0.64 | S1PR2 (0.78) | S1PR2 | |
| SCHEMBL23908893 | 0.64 | S1PR2 (0.57) | S1PR2 | |
| SCHEMBL23966785 | 0.63 | S1PR2 (0.51) | S1PR2 | |
| SCHEMBL23908861 | 0.61 | S1PR2 (0.76) | S1PR2 | |
| SCHEMBL23908822 | 0.60 | S1PR2 (0.54) | S1PR2 | |
| SCHEMBL23914852 | 0.58 | XDH (0.43) | S1PR2 | |
| SCHEMBL23382146 | 0.56 | KDM4E (0.48) | HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |