Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 8/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23915323 | 0.88 | S1PR2 (0.54) | S1PR2IDH1 | |
| SCHEMBL23908995 | 0.82 | S1PR2 (0.60) | S1PR2IDH1 | |
| SCHEMBL23915007 | 0.78 | S1PR2 (0.49) | S1PR2FGFR4 | |
| SCHEMBL23914679 | 0.78 | S1PR2 (0.56) | S1PR2 | |
| SCHEMBL23908754 | 0.76 | S1PR2 (0.67) | S1PR2 | |
| SCHEMBL23915474 | 0.76 | S1PR2 (0.41) | S1PR2 | |
| SCHEMBL23915343 | 0.75 | S1PR2 (0.58) | S1PR2 | |
| SCHEMBL23908767 | 0.73 | S1PR2 (0.75) | S1PR2CYP2C9 | |
| SCHEMBL23915346 | 0.73 | S1PR2 (0.55) | S1PR2 | |
| SCHEMBL23966617 | 0.72 | S1PR2 (0.51) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |