Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673607 | 0.90 | HPGD (0.79) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL19255255 | 0.90 | HPGD (0.79) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL14013741 | 0.83 | HPGD (0.74) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL9337868 | 0.80 | SMN1; SMN2 (0.95) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL28668503 | 0.80 | SMN1; SMN2 (0.95) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL38658755 | 0.79 | SMN1; SMN2 (0.91) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL30846691 | 0.77 | HPGD (0.96) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL10587847 | 0.76 | ALDH1A1 (0.83) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL7693790 | 0.75 | SMN1; SMN2 (0.77) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL6549000 | 0.75 | SMN1; SMN2 (0.84) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225627-B1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | UNIV NORTHWEST (CN) | 2021-11-03 | — | — | EP | disclosed |