Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18739906 | 0.80 | AHR (0.32) | AHRHTTCYP24A1ALDH1A1 | |
| SCHEMBL14612984 | 0.78 | AHR (0.30) | AHR | |
| SCHEMBL19333898 | 0.77 | CYP24A1 (0.32) | AHRCYP24A1 | |
| SCHEMBL8045233 | 0.76 | HTT (0.39) | AHRHTTCYP24A1MAPTALDH1A1 | |
| SCHEMBL22606807 | 0.74 | AHR (0.35) | AHRHTTCYP24A1ALDH1A1 | |
| Iodomethane SCHEMBL22712578 | 0.73 | AHR (0.37) | AHRHTTCYP24A1MAPTALDH1A1 | |
| SCHEMBL14825034 | 0.72 | AHR (0.35) | AHRHTTCYP24A1MAPTALDH1A1 | |
| SCHEMBL165658 | 0.72 | HTT (0.40) | AHRHTTALDH1A1 | |
| SCHEMBL1171099 | 0.72 | AHR (0.42) | AHRHTTALDH1A1 | |
| SCHEMBL9913328 | 0.70 | CYP24A1 (0.37) | AHRHTTCYP24A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161843-B2 | Fused heterocyclic compound and composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161843-B2 | Fused heterocyclic compound and composition containing same | C5, C9, NR4A1 | AHR 100/4885HTT 1203/4885CYP24A1 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.