Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL22712578 | 0.96 | AHR (0.37) | HTTAHRALDH1A1HSD17B10NFKB1 | |
| SCHEMBL1171099 | 0.82 | AHR (0.42) | HTTAHRALDH1A1TBXAS1EGLN3 | |
| SCHEMBL165658 | 0.82 | HTT (0.40) | HTTAHRALDH1A1HSD17B10NFKB1 | |
| SCHEMBL17154289 | 0.80 | AHR (0.39) | HTTAHRALDH1A1TBXAS1MAPT | |
| SCHEMBL9913328 | 0.80 | CYP24A1 (0.37) | HTTAHRALDH1A1TBXAS1MAPT | |
| SCHEMBL10951816 | 0.79 | AHR (0.49) | AHRALDH1A1TBXAS1EGLN3LMNA | |
| SCHEMBL28857423 | 0.77 | AHR (0.37) | HTTAHRALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL14123361 | 0.77 | AHR (0.48) | HTTAHRALDH1A1TBXAS1EGLN3 | |
| SCHEMBL22606807 | 0.77 | AHR (0.35) | HTTAHRALDH1A1TBXAS1LMNA | |
| SCHEMBL23967494 | 0.76 | AHR (0.34) | HTTAHRALDH1A1MAPTCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270695-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | J. MICHAEL BISHOP INSTITUTE OF CANCER RESEARCH (CN) | 2024-08-15 | — | — | US | disclosed |
| EP-4277897-A1 | FUSED AZEPINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | Chengdu Anticancer Bioscience, Ltd. (CN) | 2023-11-22 | — | — | EP | disclosed |
| CN-116710442-A | Compounds, compositions and methods for treating disorders | 成都安泰康赛生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022152097-A1 | FUSED AZEPINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | Chengdu Anticancer Bioscience, Ltd. (CN) | 2022-07-21 | — | — | WO | disclosed |
| US-20200375983-A1 | A PROCESS FOR THE PREPARATION OF CARIPRAZINE HYDROCHLORIDE | AUROBINDO PHARMA LTD (IN) | 2020-12-03 | — | — | US | disclosed |
| US-9718795-B2 | 1,4-cyclohexylamine derivatives and processes for the preparation thereof | CHEMO RESEARCH, S.L. (ES) | 2017-08-01 | — | — | US | disclosed |
| US-9718795-B2 | 1,4-cyclohexylamine derivatives and processes for the preparation thereof | CHEMO RESEARCH, S.L. (ES) | 2017-08-01 | — | — | US | disclosed |
| EP-3057942-B1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RES S L (ES) | 2017-06-14 | — | — | EP | disclosed |
| US-9593125-B2 | Heterocyclic flavone derivatives, compositions, and methods related thereto | EMORY UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160257661-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RESEARCH, S.L. (ES) | 2016-09-08 | — | — | US | disclosed |
| WO-2008057857-A1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |
| CN-1086701-C | Chloropyridylcarbonylazoles and fungicides for agriculture and horticulture | BAYER AGROCHEM KK (JP) | 2002-06-26 | — | — | CN | disclosed |
| EP-0866365-B1 | Improved hardening of hydrophilic colloids | AGFA GEVAERT NV (BE) | 2000-06-21 | — | — | EP | disclosed |
| EP-0671655-B1 | Improved hardening of hydrophylic colloids with imidazolium and triazine combinations | AGFA GEVAERT NV (BE) | 2000-06-21 | — | — | EP | disclosed |
| EP-0866365-A1 | Improved hardening of hydrophilic colloids | Sterling Diagnostic Imaging, Inc. (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5807668-A | IMIDAZOLIUM COMPOUND AND POLYHYDROXY ACCELERATOR; PHOTOGRAPHY | STERLING DIAGNOSTIC IMAGING, INC. (US) | 1998-09-15 | — | — | US | disclosed |
| CN-1147505-A | Chloropyridylcarbonylazoles and fungicides for agriculture and horticulture | BAYER AGROCHEM KK (JP) | 1997-04-16 | — | — | CN | disclosed |
| US-5601971-A | HIGH STRENGTH, WATERPROOF; CONTAINING AN IMIDAZOLIUM AND A S-TRIAZINE COMPOUND | STERLING DIAGNSOTIC IMAGING, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0671655-A2 | Improved hardening of hydrophylic colloids with imidazolium and triazine combinations | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5378842-A | Aminocarbonyl derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270695-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CYP27A1, PNLIP, GOT2 | HTT 428/4885AHR 1123/4885ALDH1A1 461/4885 |
| US-20160257661-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CYP4Z1, PNMT, HTR5A | HTT 1036/4885AHR 429/4885ALDH1A1 518/4885 |
| US-20200375983-A1 | A PROCESS FOR THE PREPARATION OF CARIPRAZINE HYDROCHLORIDE | ADRA2A, ADRA2C, HDAC2 | HTT 316/4885AHR 288/4885ALDH1A1 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.