Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 4/20 | 0.65 |
| ▸ | PTK6 | Q13882 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.54 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.50 |
| ▸ | GABRE | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL15645643 | 0.82 | ERBB2 (0.61) | ERBB2PTK6MEN1MAPTKMT2A | |
| SCHEMBL7219030 | 0.78 | AURKA (0.68) | ERBB2PTK6MAPTALKUTS2R | |
| SCHEMBL16011809 | 0.78 | ALK (0.54) | ERBB2PTK6ALKUTS2RGABRA1 | |
| SCHEMBL17559198 | 0.78 | ALK (0.54) | ERBB2PTK6ALKUTS2RGABRA1 | |
| SCHEMBL675631 | 0.78 | AURKA (0.68) | ERBB2PTK6ALKUTS2RGABRP | |
| SCHEMBL31240940 | 0.78 | AURKA (0.68) | ERBB2PTK6ALKUTS2RGABRP | |
| SCHEMBL6306638 | 0.75 | KDM4E (0.57) | ERBB2MEN1MAPTKMT2AKDM4E | |
| SCHEMBL22433744 | 0.75 | ERBB2 (0.50) | ERBB2MEN1MAPTKMT2AGABRP | |
| SCHEMBL13100676 | 0.74 | KDM4E (0.59) | ERBB2MEN1MAPTKMT2AUTS2R | |
| SCHEMBL13209220 | 0.74 | EGFR (0.57) | ERBB2MEN1MAPTKMT2AALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189052-B1 | CAMKII INHIBITORS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2021-11-03 | — | — | EP | disclosed |