SCHEMBL23968659

SCHEMBL23968659

CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H]1CC[C@H](CN)CC1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PLG P00747 16/20 0.60
▸ PRSS1 P07477 15/20 0.60
▸ PRSS2 P07478 15/20 0.60
▸ PRSS3 P35030 15/20 0.60
▸ FOLH1 Q04609 4/20 0.56
▸ PLAU P00749 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29335284 1.00 PLG (0.60) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL29678794 1.00 PLG (0.60) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL29679171 1.00 PLG (0.60) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL22878034 0.98 PLG (0.58) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL17997384 0.98 PLG (0.58) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL22139424 0.97 FOLH1 (0.61) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL25963746 0.97 PLG (0.57) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL22883092 0.97 FOLH1 (0.61) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL27049989 0.97 FOLH1 (0.61) PLGPRSS1PRSS2PRSS3FOLH1
SCHEMBL24455555 0.94 PLG (0.56) PLGPRSS1PRSS2PRSS3FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11160886-B2 Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds BRACCO IMAGING SPA (IT) 2021-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160886-B2 Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds PNP, TK1, NT5E PLG 110/4885PRSS1 909/4885PRSS2 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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