SCHEMBL23968958

SCHEMBL23968958

N#CC(C#N)=C1c2cc(OC(F)(F)F)c(-c3cccc(F)c3)cc2-c2cc(-c3cccc(F)c3)c(OC(F)(F)F)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
SCN9A Q15858 9/20 0.33
DHODH Q02127 2/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ESR2 Q92731 1/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NT5E P21589 1/20 0.32
PTPN1 P18031 1/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
FFAR1 O14842 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21917313 0.87 BACE1 (0.37) KDM4ESCN9AADORA2AADORA1MAPT
SCHEMBL23969088 0.86 KDM4E (0.46) KDM4ERXFP1SCN9ADHODHMAPT
SCHEMBL23968957 0.86 PDE3B (0.37) PDK2DHODHMAPT
SCHEMBL21917113 0.85 PDE3B (0.37) PDK2DHODHMAPT
SCHEMBL23969073 0.84 PDE2A (0.39) SCN9AMAPTFFAR1
SCHEMBL23968956 0.82 PDK2 (0.32) PDK2SCN9AMAPT
SCHEMBL21917112 0.81 TRPA1 (0.37) SCN9ADHODHADORA2AADORA1ESR2
SCHEMBL23968999 0.81 KDM4E (0.33) KDM4EMAPTL3MBTL1
SCHEMBL12149348 0.81 MAPT (0.36) MAPTCYP3A4
SCHEMBL23968920 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 PDK2 1589/4885KDM4E 664/4885HPGD 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.