Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.42 |
| ▸ | ACACA | Q13085 | 9/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969272 | 1.00 | ACACB (0.42) | ACACBACACAKAT2BBAZ2B | |
| SCHEMBL18909764 | 0.81 | ACACB (0.42) | ACACBACACA | |
| SCHEMBL18908171 | 0.81 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL23969042 | 0.81 | MEN1 (0.45) | ACACBACACAKAT2BBAZ2B | |
| SCHEMBL17580298 | 0.80 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL21980409 | 0.80 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL17580347 | 0.80 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL14945398 | 0.80 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL21816549 | 0.80 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL14945397 | 0.80 | ACACB (0.47) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904357-A1 | SPIRO COMPOUND AND MEDICAL USES THEREOF | The National Institutes of Pharmaceutical R&D Co., Ltd (CN) | 2021-11-03 | — | — | EP | disclosed |