SCHEMBL21980409

SCHEMBL21980409

COc1ccccc1C(CBr)OC1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 14/20 0.45
ACACA Q13085 10/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18909796 1.00 ACACB (0.45) ACACBACACA
SCHEMBL29354548 1.00 ACACB (0.45) ACACBACACA
SCHEMBL30901794 1.00 ACACB (0.45) ACACBACACA
SCHEMBL18908171 0.87 ACACB (0.44) ACACBACACA
SCHEMBL14945397 0.86 ACACB (0.47) ACACBACACA
SCHEMBL14945398 0.86 ACACB (0.47) ACACBACACA
SCHEMBL21816549 0.86 ACACB (0.47) ACACBACACA
SCHEMBL29642175 0.86 ACACB (0.47) ACACBACACA
SCHEMBL17580347 0.86 ACACB (0.43) ACACBACACA
SCHEMBL17580298 0.86 ACACB (0.43) ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111484504-B Optical isomer of ACC inhibitor and application thereof 南京圣和药业股份有限公司 2024-05-10 CN disclosed
CN-116745299-A Thienopyrimidine derivatives 正大天晴药业集团股份有限公司 2023-09-12 CN disclosed
EP-4071153-B1 CRYSTAL FORM OF THIENO[2,3-C]PYRIDAZINE-4(1H)-ONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF ZHANGZHOU PIEN TZE HUANG PHARM (CN) 2023-08-23 EP disclosed
EP-4071154-B1 CRYSTAL FORM AS INHIBITOR OF ACC1 AND ACC2, AND PREPARATION METHOD THEREFOR AND USE THEREOF ZHANGZHOU PIEN TZE HUANG PHARM (CN) 2023-08-23 EP disclosed
CN-114599654-B ACC inhibitor and application thereof 南京瑞捷医药科技有限公司 2023-07-04 CN disclosed
CN-116354983-A Phenyl substituted compound, preparation method and application thereof 南京汇诚制药有限公司 2023-06-30 CN disclosed
CN-116354982-A Preparation method of ACC inhibitor 南京汇诚制药有限公司 2023-06-30 CN disclosed
CN-116354984-A Preparation method of phenyl substituted ACC inhibitor and intermediate thereof 南京汇诚制药有限公司 2023-06-30 CN disclosed
EP-3660023-B1 THIENOPYRIMIDINEDIONE COMPOUNDS AS ACC INHIBITORS AND USE THEREOF NANJING SANHOME PHARMACEUTICAL CO LTD (CN) 2023-03-08 EP disclosed
EP-4056574-A1 ACC INHIBITOR AND USE THEREOF Nanjing Ruijie Pharma Co., Ltd. (CN) 2022-09-14 EP disclosed
CN-113968872-A Preparation method of phenyl substituted ACC inhibitor 南京圣和药业股份有限公司 2022-01-25 CN disclosed
CN-113967213-A Composition containing phenyl substituted ACC inhibitor and application thereof 南京圣和药业股份有限公司 2022-01-25 CN disclosed
US-11186587-B2 Compound as ACC inhibitor and use thereof NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) 2021-11-30 US disclosed
WO-2021110138-A1 CRYSTAL FORM OF THIENO[2,3-C]PYRIDAZINE-4(1H)-ONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 漳州片仔癀药业股份有限公司 2021-06-10 WO disclosed
CN-112778325-A ACC inhibitor and application thereof 南京瑞捷医药科技有限公司 2021-05-11 CN disclosed
CN-111848678-A Phosphorus-containing thienopyrimidine derivatives 正大天晴药业集团股份有限公司 2020-10-30 CN disclosed
CN-111484504-A Optical isomer of ACC inhibitor and application thereof 南京圣和药业股份有限公司 2020-08-04 CN disclosed
EP-3660023-A1 COMPOUND AS ACC INHIBITOR AND USE THEREOF Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) 2020-06-03 EP disclosed
US-20200165265-A1 COMPOUND AS ACC INHIBITOR AND USE THEREOF NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) 2020-05-28 US disclosed
CN-110959007-A Compounds as ACC inhibitors and uses thereof 南京圣和药业股份有限公司 2020-04-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165265-A1 COMPOUND AS ACC INHIBITOR AND USE THEREOF ACACA, ACACB, ACAT2 ACACB 2/4885ACACA 1/4885
US-11186587-B2 Compound as ACC inhibitor and use thereof ACACA, ACACB, ACAT2 ACACB 2/4885ACACA 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.