Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575613 | 0.89 | MEN1 (0.53) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL9684530 | 0.85 | MEN1 (0.47) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL12391214 | 0.82 | TSHR (0.43) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL474087 | 0.81 | MEN1 (0.44) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL4583913 | 0.81 | CYP3A4 (0.54) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL28659370 | 0.80 | MEN1 (0.47) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL27850207 | 0.80 | MEN1 (0.47) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL13433189 | 0.80 | MEN1 (0.47) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL13575578 | 0.80 | PPARD (0.48) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL14570495 | 0.80 | TSHR (0.42) | MEN1GAACYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801254-B | Polypropylene catalyst and preparation method thereof | 中国石油天然气股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-113801254-A | Polypropylene catalyst and preparation method thereof | 中国石油天然气股份有限公司 | 2021-12-17 | — | — | CN | claimed |
| EP-3904357-A1 | SPIRO COMPOUND AND MEDICAL USES THEREOF | The National Institutes of Pharmaceutical R&D Co., Ltd (CN) | 2021-11-03 | — | — | EP | disclosed |