Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785356 | 0.90 | TSHR (0.40) | HDAC6SLC6A5CA1CA2TSHR | |
| SCHEMBL21109914 | 0.85 | TSHR (0.36) | HDAC6SLC6A5TSHRPAOXMAOA | |
| SCHEMBL20376165 | 0.85 | TSHR (0.36) | HDAC6SLC6A5TSHRPAOXMAOA | |
| SCHEMBL16357783 | 0.81 | TDP1 (0.43) | CA12CA1CA2CA9MAOA | |
| SCHEMBL25554818 | 0.80 | GAA (0.44) | TSHR | |
| SCHEMBL14978144 | 0.77 | TSHR (0.42) | HDAC6SLC6A5TSHRPAOXKDM4A | |
| SCHEMBL22112002 | 0.74 | SLC6A5 (0.37) | HDAC6SLC6A5TSHRPAOXMAOA | |
| SCHEMBL18736144 | 0.74 | TSHR (0.40) | HDAC6SLC6A5TSHRPAOXKDM4A | |
| SCHEMBL30271168 | 0.74 | TSHR (0.44) | SLC6A5TSHRPAOXKDM4AHIF1A | |
| SCHEMBL24682168 | 0.74 | TSHR (0.34) | HDAC6SLC6A5TSHRKDM4AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160874-B2 | Glycoengineered antibody drug conjugates | GENZYME CORPORATION (US) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160874-B2 | Glycoengineered antibody drug conjugates | CD2BP2, B3GAT3, SIGLEC7 | HDAC6 861/4885SLC6A5 2477/4885CA12 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.