SCHEMBL2396919

SCHEMBL2396919

CCCCO[SiH2]C1CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PDK1 Q15118 1/20 0.34
SIGMAR1 Q99720 1/20 0.33
EPHX1 P07099 1/20 0.32
CYP1A2 P05177 1/20 0.31
RAB9A P51151 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL905670 0.96 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1TDP1PDK1SIGMAR1
SCHEMBL3822383 0.95 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1EPHX1
SCHEMBL28435099 0.95 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1EPHX1
SCHEMBL2925717 0.95 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1EPHX1
SCHEMBL2774309 0.95 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1EPHX1
SCHEMBL3701598 0.95 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1EPHX1
SCHEMBL3259228 0.91 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL3746676 0.88 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1TDP1
SCHEMBL10356323 0.86 ALDH1A1 (0.32) SMN1; SMN2ALDH1A1TDP1
SCHEMBL169746 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6830816-B2 For preparing lacquer DEGUSSA AG (DE) 2004-12-14 US claimed
US-20040096774-A1 Demonstration kit and method for enhancing and/or demonstrating photoactive properties PPG INDUSTRIES OHIO INC. 2004-05-20 US claimed
US-20030008974-A1 Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings DEGUSSA AG (DE) 2003-01-09 US claimed
EP-1249470-A2 Highly filled pasty siliconorganic nano and/or microhybridcapsules containing composition for scratch and/or abrasion resistant coatings Degussa AG (DE) 2002-10-16 EP claimed
JP-8286002-A None JP disclosed
JP-7152156-A None JP disclosed
US-8012578-B2 Method for producing composite materials DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) 2011-09-06 US disclosed
US-20100193219-A1 TRANSPARENT CONDUCTOR AND METHOD FOR PRODUCING THE SAME TDK CORPORATION (JP) 2010-08-05 US disclosed
EP-0970985-B1 Surface modified flame retardants, process for their preparation and use thereof EVONIK DEGUSSA GMBH (DE) 2009-07-29 EP disclosed
US-20090155562-A1 Method for Producing Composite Materials DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) 2009-06-18 US disclosed
US-6830816-B2 For preparing lacquer DEGUSSA AG (DE) 2004-12-14 US disclosed
US-6767982-B2 REACTING IN A FIRST STAGE AN ORGANOTRICHLOROSILANE OR A MIXTURE, WATER AND AN ALCOHOL AT 0-150 DEGREES C.; HYDROGEN CHLORIDE PRODUCT REMOVED; CRUDE PRODUCT TRANSFERRED TO REACTION DISTILLATION COLUMN; BOTTOMS RECOVERED DEGUSSA AG (DE) 2004-07-27 US disclosed
US-20030008974-A1 Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings DEGUSSA AG (DE) 2003-01-09 US disclosed
US-6444315-B1 ENCAPSULATION OF FLAME RETARDER DEGUSSA AG (DE) 2002-09-03 US disclosed
US-20020086907-A1 Continuous manufacturing process for organoalkoxysiloxanes DEGUSSA AG (DE) 2002-07-04 US disclosed
EP-0970985-A1 Surface modified flame retardants, process for their preparation and use thereof Degussa-Hüls Aktiengesellschaft (DE) 2000-01-12 EP disclosed
JP-H08286002-A PRODUCTION OF MICROLENS OKI ELECTRIC IND CO LTD 1996-11-01 JP disclosed
JP-H07152156-A RESIN COMPOSITION OKI ELECTRIC IND CO LTD 1995-06-16 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086907-A1 Continuous manufacturing process for organoalkoxysiloxanes MED1, C9, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 SMN1; SMN2 780/4885ALDH1A1 2070/4885TDP1 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.