SCHEMBL2396923

SCHEMBL2396923

Cc1cc(Cl)cc(C(=O)C(=O)O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.44
MALT1 Q9UDY8 4/20 0.38
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
NTRK1 P04629 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
PSD A5PKW4 1/20 0.33
SORT1 Q99523 1/20 0.33
DRD4 P21917 1/20 0.33
F10 P00742 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
NPC1 O15118 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28836651 0.94 DHODH (0.45) DHODHMALT1KMT2AMEN1NTRK1
SCHEMBL30473348 0.94 DHODH (0.45) DHODHMALT1KMT2AMEN1NTRK1
SCHEMBL902720 0.93 DHODH (0.46) DHODHMALT1KMT2AMEN1TRPV1
SCHEMBL28867325 0.92 DHODH (0.45) DHODHMALT1KMT2AMEN1TRPV1
SCHEMBL17644462 0.91 DHODH (0.43) DHODHMALT1KMT2AMEN1NTRK1
SCHEMBL2396376 0.91 DHODH (0.43) DHODHMALT1KMT2AMEN1NTRK1
SCHEMBL15984455 0.91 DHODH (0.44) DHODHMALT1NTRK1TRPV1PSD
SCHEMBL29377193 0.91 DHODH (0.44) DHODHMALT1NTRK1TRPV1PSD
Chlorantraniliprole SCHEMBL29551 0.91 DHODH (0.44) DHODHMALT1NTRK1TRPV1PSD
Chlorantraniliprole SCHEMBL29363261 0.91 DHODH (0.44) DHODHMALT1NTRK1TRPV1PSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8012499-B2 Anthranilamides for controlling invertebrate pests E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-06 US claimed
US-20090269300-A1 Anthranilamides for Controlling Invertebrate Pests FINKELSTEIN BRUCE LAWRENCE 2009-10-29 US claimed
EP-1924575-A1 ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS E.I.Du pont de nemours and company (US) 2008-05-28 EP claimed
WO-2007024833-A1 ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO claimed
US-8012499-B2 Anthranilamides for controlling invertebrate pests E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-06 US disclosed
US-20090269300-A1 Anthranilamides for Controlling Invertebrate Pests FINKELSTEIN BRUCE LAWRENCE 2009-10-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090269300-A1 Anthranilamides for Controlling Invertebrate Pests CYB5R3, CBR3, ANTXR2 DHODH 2158/4885MALT1 2601/4885KMT2A 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.