Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23972056 | 0.86 | S1PR1 (0.44) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL25667318 | 0.83 | PPARG (0.42) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL23965712 | 0.80 | NPC1 (0.33) | NPC1RAB9APPARGPPARAKMT2A | |
| SCHEMBL23972068 | 0.80 | HIF1A (0.48) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL23971687 | 0.79 | HIF1A (0.43) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL23971616 | 0.79 | PPARG (0.46) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL23971866 | 0.78 | HIF1A (0.41) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL23971900 | 0.76 | NPC1 (0.36) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL25551565 | 0.76 | HIF1A (0.38) | S1PR1NPC1RAB9APPARGPPARA | |
| SCHEMBL23971868 | 0.76 | HIF1A (0.38) | S1PR1NPC1RAB9APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903582-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |