Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965627 | 0.89 | HIF1A (0.34) | NPC1RAB9APPARGMAPTKMT2A | |
| SCHEMBL23971874 | 0.86 | HIF1A (0.37) | NPC1RAB9APPARGMAPTKMT2A | |
| SCHEMBL23965633 | 0.83 | SMN1; SMN2 (0.33) | NPC1RAB9APPARGKMT2ASMN1; SMN2 | |
| SCHEMBL23971876 | 0.80 | HIF1A (0.46) | NPC1RAB9APPARGKMT2ASMN1; SMN2 | |
| SCHEMBL23969509 | 0.80 | S1PR1 (0.45) | NPC1RAB9APPARGKMT2ASMN1; SMN2 | |
| SCHEMBL23971593 | 0.79 | RAB9A (0.35) | NPC1RAB9APPARGKMT2ASMN1; SMN2 | |
| SCHEMBL23971622 | 0.78 | ALDH1A1 (0.38) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25551516 | 0.78 | HIF1A (0.35) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL25598089 | 0.77 | NPC1 (0.36) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL23971989 | 0.77 | HIF1A (0.37) | NPC1RAB9APPARGMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903583-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |