Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 19/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD5 | P21918 | 3/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR1E | P28566 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616769 | 1.00 | DRD1 (0.48) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15688312 | 0.90 | DRD1 (0.48) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15688472 | 0.89 | DRD1 (0.49) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL29616683 | 0.89 | DRD1 (0.49) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15688322 | 0.81 | DRD1 (0.59) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15688349 | 0.81 | DRD1 (0.46) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15688267 | 0.81 | DRD1 (0.63) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15688482 | 0.81 | DRD1 (0.55) | DRD1TRPA1CHRM2ADRB1HTR1A | |
| SCHEMBL15698797 | 0.78 | DRD1 (0.66) | DRD1CHRM2ADRB1HTR1AADRA2A | |
| SCHEMBL22693462 | 0.78 | DRD1 (0.44) | DRD1TRPA1CHRM2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717025-B1 | IMAGING AGENTS | UCB Biopharma SRL (BE) | 2021-11-03 | — | — | EP | disclosed |