Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 19/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688472 | 1.00 | DRD1 (0.49) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL15688312 | 0.89 | DRD1 (0.48) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL29616769 | 0.89 | DRD1 (0.48) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL23969546 | 0.89 | DRD1 (0.48) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL15688349 | 0.82 | DRD1 (0.46) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL15688482 | 0.82 | DRD1 (0.55) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL15688267 | 0.82 | DRD1 (0.63) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL15688322 | 0.80 | DRD1 (0.59) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL15688624 | 0.79 | DRD1 (0.48) | DRD1TRPA1ADRB2CHRM2ADRB1 | |
| SCHEMBL17224568 | 0.76 | MAOA (0.46) | DRD1TRPA1ADRB2CHRM2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343737-A1 | Imaging Agents | UCB Biopharma SRL (BE) | 2024-10-17 | — | — | US | disclosed |
| US-20220162221-A1 | Imaging Agents | UCB Biopharma SRL (BE) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162221-A1 | Imaging Agents | MPI, TMEM14C, NECTIN4 | DRD1 2957/4885TRPA1 4091/4885ADRB2 1629/4885 |
| US-20240343737-A1 | Imaging Agents | MPI, TMEM14C, NECTIN4 | DRD1 2957/4885TRPA1 4091/4885ADRB2 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.