Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.51 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969580 | 0.86 | ELANE (0.51) | ELANECTSGTAAR1CMA1PREP | |
| SCHEMBL28866281 | 0.86 | ELANE (0.51) | ELANECTSGTAAR1CMA1PREP | |
| SCHEMBL28866278 | 0.86 | ELANE (0.51) | ELANECTSGTAAR1CMA1PREP | |
| SCHEMBL3935567 | 0.85 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL30583172 | 0.85 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL20943154 | 0.85 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL3935563 | 0.85 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL20943188 | 0.85 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL20943149 | 0.83 | ELANE (0.65) | ELANECTSGCMA1 | |
| SCHEMBL28626508 | 0.82 | ELANE (0.47) | ELANECTSGTAAR1CMA1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | PCSK9, LIPA, ACSL3 | ELANE 493/4885CTSG 780/4885TAAR1 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.