Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709172 | 0.85 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL3900981 | 0.82 | CSNK2A1 (0.70) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL3912942 | 0.82 | CSNK2A1 (0.70) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL17859694 | 0.81 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL30440667 | 0.81 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL30803440 | 0.81 | CSNK2A1 (1.00) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL17859650 | 0.81 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL27828640 | 0.78 | CSNK2A1 (0.42) | CSNK2A1FOLH1ALDH1A1HPGDTSHR | |
| SCHEMBL29712509 | 0.78 | CSNK2A1 (0.42) | CSNK2A1FOLH1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7367797 | 0.78 | CSNK2A1 (0.64) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036937-A | 2' -halobiphenyl-4-yl intermediates for the synthesis of angiotensin II antagonists | LEK PHARMACEUTICALS | 2011-04-27 | — | — | CN | claimed |
| CN-102015690-A | Catalytic carboxylation in the synthesis of angiotensin II antagonists | LEK PHARMACEUTICALS | 2011-04-13 | — | — | CN | claimed |
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| CN-102036937-A | 2' -halobiphenyl-4-yl intermediates for the synthesis of angiotensin II antagonists | LEK PHARMACEUTICALS | 2011-04-27 | — | — | CN | disclosed |
| CN-102015690-A | Catalytic carboxylation in the synthesis of angiotensin II antagonists | LEK PHARMACEUTICALS | 2011-04-13 | — | — | CN | disclosed |