Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709172 | 0.81 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL3900981 | 0.79 | CSNK2A1 (0.70) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL3912942 | 0.79 | CSNK2A1 (0.70) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL15546386 | 0.79 | PTGS1 (0.44) | CSNK2A1FOLH1ESR1HCAR2 | |
| SCHEMBL23969675 | 0.78 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL30803440 | 0.78 | CSNK2A1 (1.00) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL30440667 | 0.78 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL17859694 | 0.78 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL17859650 | 0.78 | CSNK2A1 (0.68) | CSNK2A1CYP2A6CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL11839181 | 0.77 | CSNK2A1 (0.62) | CSNK2A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344464-B1 | Use of tetrahydropyridine derivatives to prepare medicines for treating diseases causing demyelination | SANOFI-SYNTHELABO (FR) | 2002-02-05 | — | — | US | disclosed |
| US-6342505-B1 | inhibiting apoptosis using xaliproden hydrochloride, or other tetrahydropyridine derivatives | SANOFI-SYNTHELABO (FR) | 2002-01-29 | — | — | US | disclosed |