Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059186 | 0.81 | HRH3 (0.38) | TAAR1HDAC3HDAC6 | |
| SCHEMBL21770321 | 0.81 | KDM4E (0.31) | CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21770155 | 0.81 | PRSS1 (0.35) | RAB9ANPC1MEN1KMT2ACYP2C9 | |
| SCHEMBL27401957 | 0.76 | HPGD (0.40) | RAB9ANPC1HPGDMEN1APAF1 | |
| SCHEMBL14326960 | 0.74 | SMN1; SMN2 (0.33) | RAB9ANPC1MEN1APAF1ALDH1A1 | |
| SCHEMBL14627607 | 0.73 | KMT2A (0.50) | RAB9ANPC1MEN1ALDH1A1GAA | |
| SCHEMBL16642045 | 0.73 | KMT2A (0.50) | RAB9ANPC1MEN1ALDH1A1GAA | |
| SCHEMBL23969707 | 0.72 | CYP2C9 (0.41) | RAB9ANPC1HPGDMEN1APAF1 | |
| SCHEMBL13373993 | 0.71 | CYP2A6 (0.46) | RAB9ANPC1HPGDMEN1APAF1 | |
| SCHEMBL3560236 | 0.71 | ALDH1A1 (0.50) | RAB9ANPC1HPGDMEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |