Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374192 | 0.85 | MAOB (0.50) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL8374190 | 0.85 | MAOB (0.50) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL8374191 | 0.85 | MAOB (0.50) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL9217999 | 0.81 | MAOB (0.46) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL9222324 | 0.81 | MAOB (0.46) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL9217995 | 0.81 | MAOB (0.46) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL12203818 | 0.77 | MAOB (0.42) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL3669608 | 0.76 | PAM (0.55) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL5974329 | 0.76 | PAM (0.55) | IDO1NOS1NOS3NOS2MAOB | |
| SCHEMBL8541497 | 0.75 | MAOB (0.50) | IDO1NOS1NOS3NOS2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |