Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865805 | 0.92 | ALDH1A1 (0.53) | LMNAMAPTALDH1A1RORCNPC1 | |
| SCHEMBL21127002 | 0.88 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1RORCKMT2A | |
| SCHEMBL26243113 | 0.83 | ALDH1A1 (0.42) | LMNAMAPTALDH1A1RORCKMT2A | |
| SCHEMBL10175378 | 0.82 | ALDH1A1 (0.42) | LMNAMAPTALDH1A1KMT2AEPHX1 | |
| SCHEMBL10175373 | 0.82 | ALDH1A1 (0.42) | LMNAMAPTALDH1A1KMT2AEPHX1 | |
| SCHEMBL26628691 | 0.82 | EPHX1 (0.43) | LMNAMAPTALDH1A1RORCEPHX1 | |
| SCHEMBL15308549 | 0.79 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1RORCNPC1 | |
| SCHEMBL15308496 | 0.79 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1RORCNPC1 | |
| Hydrochloric Acid SCHEMBL28225853 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27010019 | 0.75 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1RORCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |