Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379454 | 0.81 | ERAP2 (0.41) | PSMB1PSMB5KDM4EALDH1A1HPGD | |
| SCHEMBL18379422 | 0.78 | ERAP2 (0.42) | PSMB1HSD17B10PSMB5KDM4EALDH1A1 | |
| SCHEMBL4327817 | 0.75 | EPOR (0.55) | EPORHPGD | |
| SCHEMBL20382952 | 0.75 | MAPK14 (0.47) | POLBGRM2 | |
| Hydrochloric Acid SCHEMBL4279930 | 0.75 | EPOR (0.54) | EPORHPGD | |
| Hydrochloric Acid SCHEMBL4469753 | 0.74 | MAPK14 (0.55) | APPMTNR1APSMB1PSMB5POLB | |
| SCHEMBL4320373 | 0.73 | EPOR (0.52) | EPOR | |
| SCHEMBL8102831 | 0.73 | KDM4E (0.49) | MTNR1APOLBMTNR1BKDM4EHPGD | |
| SCHEMBL20382945 | 0.73 | MAPK14 (0.47) | ALDH1A1GRM2 | |
| SCHEMBL20382950 | 0.73 | MAPK14 (0.47) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319950-B1 | VICINAL PRIMARY DIAMINES ASSOCIATED WITH METAL AND/OR FREE RADICAL CHELATION MOTIFS, AND ACTIVE AGAINST CARBONYL AND OXIDATIVE STRESS, AND USE THEREOF | UNIV AMIENS PICARDIE JULES VERNE (FR) | 2021-11-03 | — | — | EP | disclosed |