Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106183 | 0.93 | KDM4E (0.51) | KDM4ENR5A1MAPTHTTNPC1 | |
| SCHEMBL8102567 | 0.89 | BRD4 (0.54) | KDM4ENR5A1MAPTHTTNPC1 | |
| SCHEMBL9512037 | 0.85 | KDM4E (0.44) | KDM4ENR5A1MAPTHTTNPC1 | |
| SCHEMBL8106275 | 0.83 | IL1RN (0.49) | KDM4EMAPTHTTNPC1IL1RN | |
| SCHEMBL8126132 | 0.82 | MTNR1A (0.45) | KDM4EMAPTMTNR1AMTNR1BRXFP1 | |
| SCHEMBL20382946 | 0.80 | MAPK14 (0.49) | MAPTIL1RNERAP2ERAP1BRD4 | |
| SCHEMBL20382949 | 0.80 | MAPK14 (0.50) | MAPTHTTHPGDKMT2A | |
| SCHEMBL8100824 | 0.79 | MAPK14 (0.49) | MAPTIL1RNERAP2ERAP1POLB | |
| SCHEMBL621806 | 0.79 | IL1RN (0.45) | KDM4EMAPTHTTNPC1RXFP1 | |
| SCHEMBL8102437 | 0.77 | ERAP2 (0.60) | KDM4ENR5A1MAPTHTTIL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36831-E | TREATMENT OF IRON DEFICIENCY ANEMIA | BRITISH TECHNOLOGY GROUP LTD. (GB) | 2000-08-22 | — | — | US | disclosed |
| US-RE35948-E | TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1998-11-03 | — | — | US | disclosed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |
| EP-0120670-B1 | IRON III COMPLEXES OF HYDROXYPYRIDONES, AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |