Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14311723 | 0.81 | HTT (0.63) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30580520 | 0.81 | MEN1 (0.56) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30580526 | 0.80 | MEN1 (0.59) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30580525 | 0.80 | MEN1 (0.59) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3361014 | 0.78 | MEN1 (0.56) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29243887 | 0.78 | MEN1 (0.60) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29243885 | 0.78 | MEN1 (0.60) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20382964 | 0.77 | MEN1 (0.61) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30580528 | 0.76 | HTT (0.54) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21046037 | 0.76 | HTT (0.48) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319950-B1 | VICINAL PRIMARY DIAMINES ASSOCIATED WITH METAL AND/OR FREE RADICAL CHELATION MOTIFS, AND ACTIVE AGAINST CARBONYL AND OXIDATIVE STRESS, AND USE THEREOF | UNIV AMIENS PICARDIE JULES VERNE (FR) | 2021-11-03 | — | — | EP | disclosed |