Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30580521 | 0.93 | HTT (0.52) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30580520 | 0.91 | MEN1 (0.56) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30580535 | 0.87 | HTT (0.44) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30580526 | 0.83 | MEN1 (0.59) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30580525 | 0.83 | MEN1 (0.59) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30580532 | 0.81 | PTGES (0.43) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL14311723 | 0.79 | HTT (0.63) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30580538 | 0.78 | HTT (0.46) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL23969870 | 0.76 | MEN1 (0.56) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL29243824 | 0.76 | MEN1 (0.56) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621775-A | 2-amino-5-hydroxytetrahydronaphthalene derivative containing hydroxypyridone side chain, preparation and application thereof | 浙江大学 | 2023-08-22 | — | — | CN | disclosed |