Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 10/20 | 0.33 |
| ▸ | MAOA | P21397 | 8/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9897381 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL1160567 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL9920362 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL9897387 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL1160571 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL15519422 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL9897385 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL1160569 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL21030435 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB | |
| SCHEMBL15519424 | 0.75 | GAA (0.45) | ALDH1A1GAAMAPTMAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904354-A1 | NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | Perha Pharmaceuticals (FR) | 2021-11-03 | — | — | EP | disclosed |