⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550763 | 0.95 | — | — | |
| SCHEMBL28586993 | 0.80 | — | — | |
| SCHEMBL7916836 | 0.80 | — | — | |
| SCHEMBL29086318 | 0.75 | — | — | |
| SCHEMBL6933322 | 0.74 | — | — | |
| SCHEMBL28419644 | 0.74 | — | — | |
| SCHEMBL28589482 | 0.73 | — | — | |
| SCHEMBL28533105 | 0.73 | — | — | |
| SCHEMBL5248786 | 0.72 | LPAR3 (0.34) | — | |
| SCHEMBL10539415 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796012-B2 | Grating-based evanescent field molecular sensor using a thin silicon waveguide layer | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2014-08-05 | — | — | US | disclosed |
| US-20110223688-A1 | GRATING-BASED EVANESCENT FIELD MOLECULAR SENSOR USING A THIN SILICON WAVEGUIDE LAYER | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2011-09-15 | — | — | US | disclosed |
| WO-2010063116-A1 | GRATING-BASED EVANESCENT FIELD MOLECULAR SENSOR USING A THIN SILICON WAVEGUIDE LAYER | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-06-10 | — | — | WO | disclosed |