⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21388640 | 0.86 | — | — | |
| SCHEMBL11597288 | 0.67 | KMT2A (0.31) | — | |
| SCHEMBL15657996 | 0.67 | — | — | |
| SCHEMBL21009009 | 0.65 | — | — | |
| SCHEMBL5253568 | 0.65 | — | — | |
| SCHEMBL182943 | 0.65 | — | — | |
| SCHEMBL5904175 | 0.64 | CRBN (0.37) | — | |
| SCHEMBL7389049 | 0.63 | — | — | |
| SCHEMBL21740353 | 0.63 | KMT2A (0.41) | — | |
| SCHEMBL1444040 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078407-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-11160783-B2 | Multikinase inhibitors for use in the treatment of cancer | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-11-02 | — | — | US | disclosed |