SCHEMBL2397051

SCHEMBL2397051

CCO[Si]1(OCC)CCCC(CCCCN)O1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331647 0.95
SCHEMBL464869 0.88
SCHEMBL28901506 0.74 SIGMAR1 (0.40) SIGMAR1
SCHEMBL28419646 0.73 EPHX1 (0.42)
SCHEMBL27758145 0.72 EPHX1 (0.44)
SCHEMBL27737408 0.72 EPHX1 (0.44)
SCHEMBL28704031 0.72
SCHEMBL10454248 0.71 EPHX1 (0.35)
SCHEMBL29086320 0.71
SCHEMBL9236580 0.70 SIGMAR1 (0.31) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8796012-B2 Grating-based evanescent field molecular sensor using a thin silicon waveguide layer NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2014-08-05 US disclosed
US-20110223688-A1 GRATING-BASED EVANESCENT FIELD MOLECULAR SENSOR USING A THIN SILICON WAVEGUIDE LAYER NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-09-15 US disclosed
WO-2010063116-A1 GRATING-BASED EVANESCENT FIELD MOLECULAR SENSOR USING A THIN SILICON WAVEGUIDE LAYER NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2010-06-10 WO disclosed