Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688085 | 1.00 | CA2 (0.41) | CA2CYP3A4TSHR | |
| SCHEMBL28408357 | 1.00 | CA2 (0.41) | CA2CYP3A4TSHR | |
| SCHEMBL5243057 | 1.00 | CA2 (0.41) | CA2CYP3A4TSHR | |
| SCHEMBL687625 | 1.00 | CA2 (0.41) | CA2CYP3A4TSHR | |
| SCHEMBL224425 | 1.00 | — | — | |
| SCHEMBL5240827 | 1.00 | CA2 (0.41) | CA2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL28135038 | 0.94 | CA2 (0.39) | CA2CYP3A4TSHR | |
| SCHEMBL23647292 | 0.83 | CA2 (0.44) | CA2CYP3A4TSHR | |
| SCHEMBL14920 | 0.83 | CA2 (0.44) | CA2CYP3A4TSHR | |
| SCHEMBL4607864 | 0.83 | CA2 (0.44) | CA2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237528-A1 | COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2011-09-29 | — | — | US | disclosed |
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | CFTR, PKD1, PKD2 | CA2 813/4885CYP3A4 1541/4885TSHR 2802/4885 |
| US-20110237528-A1 | COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | CFTR, PKD1, PKD2 | CA2 1509/4885CYP3A4 1588/4885TSHR 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.