Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866628 | 0.72 | DHODH (0.54) | DHODHLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29281090 | 0.71 | DHODH (0.57) | DHODHLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL505544 | 0.70 | DHODH (1.00) | DHODHALDH1A1KDM4EHSD17B10 | |
| SCHEMBL17896671 | 0.67 | DHODH (0.64) | DHODHLMNAALDH1A1KDM4E | |
| SCHEMBL29308340 | 0.67 | DHODH (0.51) | DHODHALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL10175143 | 0.67 | DHODH (0.72) | DHODHLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL2394762 | 0.66 | KDM4E (0.47) | DHODHALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7425056 | 0.65 | DHODH (0.49) | DHODHALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL2013447 | 0.65 | DHODH (0.49) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4457716 | 0.65 | DHODH (0.52) | DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542533-B1 | FLUORALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THEIR USE FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER IP GMBH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2542533-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107504-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | disclosed |