Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996562 | 0.74 | TSHR (0.47) | TSHRKMT2AALDH1A1 | |
| SCHEMBL6168745 | 0.74 | LMNA (0.47) | DHODHTSHRKMT2AFABP4 | |
| SCHEMBL29308340 | 0.74 | DHODH (0.51) | DHODHTSHRKMT2AALDH1A1FABP4 | |
| SCHEMBL13387272 | 0.73 | HTR3A (0.40) | DHODH | |
| SCHEMBL13387271 | 0.73 | HTR3A (0.40) | DHODH | |
| SCHEMBL13387318 | 0.73 | HTR3A (0.40) | DHODH | |
| SCHEMBL3828558 | 0.72 | TSHR (0.83) | TSHRKMT2AALDH1A1 | |
| SCHEMBL4453299 | 0.71 | DPP4 (0.45) | DHODHKMT2AAPAF1ALDH1A1 | |
| SCHEMBL4793832 | 0.70 | DHODH (0.65) | DHODH | |
| SCHEMBL1520226 | 0.70 | KMT2A (0.62) | TSHRKMT2AAPAF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042490-A2 | Benzimidazole derivatives as vanilloid receptor antagonists | AstraZeneca AB (SE) | 2009-04-01 | — | — | EP | claimed |